Regulid, a natural weight stabilizer
STABILIZE WEIGHT AND FIGHT YO-YO EFFECT
Advantages of Regulid
Stabilize weight and fight yo-yo effect
Reduce adipocyte differentiation & increase lipolysis
Anti-inflammatory action
Based on natural extracts (vinyldithiins and allylsulfides) of organic garlic
The yo-yo dieting
Most of us are familiar with the concept of yo-yo dieting: losing weight during a crash or fad diet, and regaining it as soon as the diet is over. This cyclical pattern of weight loss and gain ultimately results in a net weight gain, with some potentially damaging effects on the body - not to mention the psychological effects of being trapped in this yo-yo pattern.
Research has shown that taking Regulid during a sensible weight loss diet, and continuing to take it for 3-6 months afterwards may help maintain the post-diet weight by inhibiting the process by which fat cells store up on fat. The specific garlic active principals in Regulid have been shown to affect the metabolism of adipocytes (fat cells) and to also have a beneficial effect on cholesterol levels, in particular Triglycerides and HDL.
Regulid Unique Composition
Regulid, thanks to a unique and innovative extraction process, offers a standardized amount of the most active sulfur compounds from garlic:
- Vinyldithiins: 1,2-vinyldithiin (1,2-DT) and 1,3-vinyldithiin (1,3-DT)
- Sulfides: Diallyldisulfide (DADS), Diallyltrisulfide (DATS), Methylallyltrisulfide (MATS).
Regulid to fight yo-yo dieting syndrome
REGULID active principals affect specific stages of the adipocyte life cycle [1].
1,2-vinyldithiin in Regulid inhibits preadipocyte differentiation and reduces lipid accumulation in maturing preadipocytes. It also triggers lipolysis in mature adipocytes, and in combination with DADS, it reinforces even more the induction of lipolysis.
Since a number of complexed interconnected cell signaling pathways are involved in regulating the adipocyte cycle, treating adipocytes with multiple natural molecules results in enhanced effects. By targeting preadipocyte differentiation, lipid filling in maturing preadipocytes and also by increasing
lipolysis, Regulid offers a complete solution for adipocyte management during dieting and also during the stabilization period following a diet.
By reducing the appearance of new adipocytes, reducing their capability for storing fat and increasing lipolysis, Regulid helps stabilize the amount of fat in the body, and reduce the unavoidable refilling of adipocytes after a diet.
Regulid to help manage metabolic syndrome
Regulid active principals have also demonstrated their positive effects on regulation of Triglycerides and Good Cholesterol (HDL) levels, in a clinical trial conducted by Bordia in 1981 [2].
This double-blind, randomized, placebo-controlled study demonstrated the efficacy of a garlic preparation (with the same composition as REGULID) on the different lipid blood fractions (in particular on TG and HDL).
Regulid Master File
Regulid is delivered with a completel scientific dossier, detailing:
bioXtract pre-clinical trials evaluating:
- the efficacy of Regulid active principal on in vitro adipocyte metabolism,
- lack of oral toxicity (acute oral toxicity tests on rats).
Bibliographical clinical data
- Bibiliographical Phase II clinical results obtained with a Regulid equivalent composition.
Regulid is a food supplement registered in Belgium and France.
[1] Keophiphath M, Priem F, Jacquemond-Collet I, Clément K, Lacasa D. 1,2-vinyldithiin from garlic inhibits differentiation and inflammation of human preadipocytes. J. Nutr. 2009; 139: 2055-2060.
[2] Bordia A. Effect of garlic on blood lipids in patients with coronary heart disease. Am. J. Clin. Nutr. 1981, 34; 2100-2103.

