Artiflex, alternative therapy for osteoarthritis
A highly bioavailable anti-inflammatory and chondroprotector
Artiflex is an innovative formulation of curcumin, known to provide relief for sufferers of osteoarthritis.
Artiflex will contribute to joint wellbeing by relieving pain, and protecting cartilage from breakdown. Taken long term, over time Artiflex will help protect cartilage and contribute to healthy joints.
Artiflex is consequently an alternative therapy for osteoarthritis.
Artiflex Formulation
Resulting from several years of Research and Development, Artiflex is an unique composition, combining curcumin and β-cyclodextrin, leading to a marked improvement in uptake, with doses of bioavailable curcumin of 3.7 mg bio-equivalent to 1,200 mg of non-complexed curcumin.
Artiflex in Osteoarthritis
bioXtract in vitro studies on curcumin show that Artiflex:
- inhibits pro-inflammatory mediators (PGE2, IL-6, IL-8) and acts on the pain of osteoarthritis,
- inhibits COX-2 but not COX-1 gene expression, and gives pain relief without unwanted gastro-intestinal side effects,
- inhibits the synthesis of NO and prevents cartilage breakdown in the joint.
Artiflex Master File
Artiflex is delivered with a complete package of information, including bioXtract proprietary:
Pre-clinical trials evaluating:
- the efficacy of Artiflex active principal on several models of osteoarthritis,
- the lack of toxicity of Artiflex (acute oral toxicity in rats),
- Caco-2 testing demonstrating improved bioavailability of curcumin.
Artiflex is a food supplement registered in Belgium and France.